Showing posts with label Remdesivir. Show all posts
Showing posts with label Remdesivir. Show all posts

Sunday, May 3, 2020

Stocks Flat As States Begin to Reopen; COVID-19 Still Wreaking Havoc on Lives, Markets

This installment of the WEEKEND WRAP is going to be one of the shortest since the onset of the coronavirus crisis because noting much of consequence occurred, other than the "breakthrough" with Gilead Science's remdesivir clinical trial.

Turns out, remdesivir, as was already known, has little effect on the virus and doesn't reduce mortality at all. The study was purposely shortened to include only the data that shows the drug reduces the time to recovery by about 30%. Big deal. You take it - at $1000 a dose - and you recover in ten days rather than 14, at a cost of some $6-8000. Yeah, great. Four fewer days with a bad cold and a big pharmacy bill.

Hydroxychloroquine with zinc supplements and healthy doses of Vitamins C, D3, and Quercetin (or red wine, onions, green tea, apples, berries) before infection will likely prevent one from contracting the virus, and, the same combination after infection (if started early) will shorten the duration and severity.

Proven.

Mainstream media and government won't allow this information to even be considered.

The release of the remdesivir story was timed to coincide with the release of first quarter GDP, which was a very disappointing -4.8 percent. It's worth noting that many mainstream economists, like those from Bank of America and Goldman Sachs, downplayed the first quarter and thought it was going to come in as a positive number, proving, once again, that expert opinions should be treated in a similar manner to online stock touts. Both are better avoided and trusting in your own gut.

Most states have at least partially re-opened their economies, lead by Georgia, Florida, Tennessee and other Southern and some Midwestern states, notably Iowa, the Dakotas, Kansas, Nebraska, Oklahoma, Missouri, Texas). Some eight states never actually issued lockdown orders in the first place.

Meanwhile New York, New Jersey, Connecticut, Massachusetts, Virginia, Michigan, California, and others are still operating under lockdown restrictions.

This Wired.com article from April 30 offer some accurate state-by-state reporting.

Stocks finished the week about where they started (see below).

Treasuries closed out the week with the 2-year note yielding 0.20%, the 10-year, 0.64%, and the 30-year, 1.27%. There was limited movement. The 2-year down two basis points, the 10-year up four, and the 30-year up 10. The curve steepened 10 basis points to 117, essentially all driven by the 30-year.

Oil seems to be stabilizing, but at a price that will slaughter some smaller producers. WTI crude finished the week at its high of $19.69 a barrel on the June contract. Predictions are for a sloppy termination of the current contract, though nothing quite like the end of the May contract when oil prices turned negative.

Precious metals continue to be massaged and depressed. Gold futures closed out on Friday at $1700.40 per troy ounce. Silver futures finished at $14.97. The gold/silver ratio stands at 113.6, near a 5000-year high. The sensible move, for investors would be to be buying silver for the foreseeable future, as premiums on both metals are high, though, on a percentage basis, the silver premiums are drastic. It's nearly impossible to purchase silver for under $20 an ounce in quantity. Smaller amounts, such as one ounce coins and bars carry premiums of 70 to 100% or higher, whereas gold premiums are about $130-160, less than 10%.

It's actually far easier to purchase silver than gold, especially on ebay, where delivery delays such as those being experienced by dealers, are cut down to a few days rather than weeks. Delivery delays are slowly abating, but minimum order sizes remain in place at many online dealers.

It appears as though stocks are going to tumble on Monday, as word leaked out that Berkshire Hathaway, the holding company of Warren Buffett, is going to be selling hard into the recent rally. A retest of the March lows could be underway as stocks finished dramatically lower Friday - which happened to be May 1 - wiping out the week's gains.

The Dow Jones Industrial Average has failed repeatedly to break through the 50% retrace line off the lows, and that could portend a significant shift in risk assessment.

At the Close, Friday, May 1, 2020:
Dow: 23,723.69, -622.03 (-2.55%)
NASDAQ: 8,604.95, -284.60 (-3.20%)
S&P 500: 2,830.71, -81.72 (-2.81%)
NYSE: 11,058.57, -313.77 (-2.76%)

For the Week:
Dow: -51.58 (-0.22%)
NASDAQ: -29.57 (-0.34%)
S&P 500: -6.03 (-0.21%)
NYSE: +40.68 (-0.37%)

Friday, May 1, 2020

The World Has Been Hoaxed; Hydroxychloroquine Works; Rent Strike, Mass Protests On Tap for May 1

April is over and done. The month that saw the WuHan Flu, coronavirus, COVID-19, SARS-COV II, or whatever you prefer calling it spread like wildfire throughout the United States and the world also produced the best performance in the S&P 500 since 1987.

As if the stock market's miraculous rebound off the March lows wasn't enough, the Fed's balance sheet, thanks to sopping up trillions in debt of all varieties - from corporate issuance to high yield (junk) to munis to the usual nasty mortgage=backed securities (MBS) and low-yielding treasuries - increased by some $2.23 trillion to a record amount of more than $6.6 trillion.

Also showing up on the national radar are people who are refusing to go back to work because they are making more on unemployment, states reopening businesses with some restrictions and precautions, Florida opening beaches while California closes them down, a GDP for the first quarter of -4.8%, and various misdirections, untruths, fabrications, and outright lies due to conflicts of interest by doctors (including the CDC's Dr. Anthony Fauci) promoting Gilead Science's remdesivir as a primary treatment of COVID-19 with little to no evidence that it does anything more than shorten the length of hospitalizations.

All the while, evidence continues to pile up showing hydroxychloroquine (HCQ) as a drug with a wide range of uses in not only diminishing the severity of coronavirus symptoms, but possibly acting as a preventive treatment, i.e., Lupus patients, who are prescribed Plaquenil (the brand name for HCQ), do not contract coronavirus.

Various studies from countries around the world have shown early use of HCQ is highly effective in combating the coronavirus, though the mainstream media refuses to report any positives about the drug, preferring to bombard the public with questionable research on remdesivir, a drug that can cost as much as $100 per dose, where HCQ can be produced in massive quantities for about a dime per dose.

Peak Prosperity's Chris Martenson, who has been doing incredible daily reporting on the crisis, has details in his latest video:



While the US continues to lurch toward some degree of normalcy at the end of a six-week near-nationwide lockdown, many questions linger, not the least of which being how badly the American public has been hoodwinked by the wealthy elite and their cohorts in government. From all appearances, it seems the public has been royally screwed this time around.

The economy is in tatters, more than 30 million lost their jobs, but what is likely going to be worse, are the millions of small businesses which have been severely hampered or outright destroyed by government overreach. Many of these businesses will not come back in the summer, or the fall. They are gone forever, and with them, their owners facing financial ruin. It will take years to undo the damage wrought by the government response to a virus that essentially affects people over 50 or those with pre-existing serious medical issues.

Friday, May 1, will offer some pushback agains the federal tyranny. There's a nationwide rent strike being waged in big cities and small, along with a May Day work stoppage promoted by employees of some of the multi-national companies that were not forced to shut down for the past six weeks, including Wal-Mart, Amazon, Target, and others. Protests will be very visible, as will the outrage expressed in Michigan, where governor Gretchen Whitmer is extending the lockdown until May 28.

Protesters there have already been storming the Capitol, and some were actually armed inside the Capitol building on Thursday, though that received scant notice on the evening TV news. This explosive situation merits closer attention, as what happens in Lansing, Michigan's capitol, may serve as a template for popular uprisings in places like Virginia, California, New York, Massachusetts, and any other state that believes they can keep the general population under lock and key indefinitely.

With warmer weather and a weekend ahead, some payback may be forthcoming from an angry, frustrated American public.

In other markets, gold and silver were beaten down as they usually are at the end of the month, though the dislocation between spot, futures, and actual prices for acquiring physical metal has completely blown up. Silver especially is out of whack, with premiums over the futures price of anywhere from 30 to 100% now commonplace. Gold premiums are still in the 10-15% range, though dealers have been and continue to impose minimums with lengthy shipping delays.

Oil markets continue to fluctuate wildly as the supply glut and demand collapse refuse to abate. Beyond giants Russia and Saudi Arabia, countries which produce oil as a primary revenue source are going to be devastated, while in the US, rig counts are plummeting as shale drilling operations are being shut down. They're unable to make money at the current prices and investors are being wiped out along with the lenders who financed operations. WTI crude, as of Friday morning is hovering just under $19 a barrel, though it's been as low as $10.64 earlier this week. The June futures contract is beginning to look like another disaster - as was the May contract - in the making.

Treasuries have been relatively unmoved during the week, though the 30-year bond has increased yield from 1.17% last Friday to 1.28% Thursday. The curve has steepened slightly, though not in any statistically meaningful way. 118 basis points covers the entire complex.

Equity futures are pointing to a very ugly open Friday, with Dow futures down more than 450 points.

Could this be the "sell in May and go away" signal? Possible, but the real fallout may not occur until late July or August when earnings and the first reading of second quarter GDP will shock the markets, not just in the United States, but globally. The Greater Depression is ramping up.

At the Close, Thursday, April 30, 2020:
Dow: 24,345.72, -288.14 (-1.17%)
NASDAQ: 8,889.55, -25.16 (-0.28%)
S&P 500: 2,912.43, -27.08 (-0.92%)
NYSE: 11,372.34, -245.89 (-2.12%)

Friday, March 20, 2020

Stocks Bounce As News Suggests Possible, Readily-Available COVID-19 Treatments May Be Effective

Considering the extreme levels of volatility lately, Thursday's trading was relatively calm. Though the VIX remained elevated, it came down from over 80 to near 70 as the day commenced.

Stocks initially were lower, but found solid footing and ramped higher by mid-morning, the NASDAQ leading the way with speculators eyeing stocks that had cratered over the past three weeks, and began establishing positions at levels they considered to be bargains.

The S&P, Dow, and NYSE composite followed gamely but trailed the red-hot NASDAQ by more than a percentage point throughout the session. It was the first in many days that stocks had not ventured more than three percent in either direction for the last nine sessions, so some might argue that volatility is cooling, though still near record levels.

Moving 900 points from the morning lows to the close, the Dow's move was impressive, considering it has been absolutely damaged the prior session with Boeing (BA) leading the way down on Wednesday with a loss of some 25%. The aircraft manufacturer was down a mere four percent on Thursday, and is sporting a positive sign in pre-market trading Friday.

Thursday's unemployment claims numbers were 281,000, up by 71,000 over the prior week, but were for the week ending March 14, so much of the coronavirus-related data had not been tabulated, but will appear next Thursday.

Goldman Sachs’ Jan Hatzius wrote in a note to clients on Thursday night, “state-level anecdotes point to an unprecedented surge in layoffs this week.” The analyst claims that figures for the week ending March 21 will show initial claims rising to roughly 2¼ million, which would be the largest increase in initial jobless claims and the highest level on record. That's not unlikely, as major cities - San Francisco and New York in particular - are at or near lockdown levels of activity with many workers furloughed or otherwise idled by warnings or edicts from city and state officials.

Philly Fed’s manufacturing activity index crashed to an eight-year low of -12.7 in March from a three-year high of 36.7 in February. This follows the NY Fed’s Empire State Manufacturing index, which also dropped at a record pace to an 11-year low.

In a research report published on Thursday, Bank of America economists predicted the U.S. economy would lose 3.5 million jobs and GDP plummeting at a 12% pace in the second quarter, also probable figures given the severity of the reaction to COVID-19.

What's keeping Wall Street open for business and possibly ending the week with a positive tone are actions taken by the Fed which are too numerous to list, but include opening swap lines to other central banks, injecting billions of dollars via repo and QE, and wide open credit lines to primary dealers.

Also, President Trump's mention of a possible treatments for the virus in his now-daily news briefing, has been getting a great deal of attention. Specifically, the president mentioned a number of possible drugs that showed promise in tests, including Gilead Sciences' remdesivir (Money Daily mentioned Gilead's product back in January as a promising treatment and the stock has responded with a run from 63 to 78 since then) and chloroquine, an inexpensive drug long used to treat malaria, which is widely available and has proven to be an effective anti-viral in clinical trials done recently in China and France.

Thus, while COVID-19 is still making its way through the population, potential treatments are promising and - in the case of chloroquine - readily available in mass quantities at extremely low cost (less than 10 cents per pill in some countries). Also emerging is data from South Korea, Italy, the United States, and elsewhere that show the vast majority of cases that result in death are people over the age of 60 with underlying health conditions such as heart conditions, diabetes, or otherwise compromised immune systems.

That's the kind of news Wall Street traders can get behind, because, if successful treatments become widely available, people could be back at work within weeks, rather than months. While various governments - including California, which late Thursday announced a state-wide stay-at-home recommendation - are trying to limit transmission via social distancing and "soft" quarantines, communities that develop "herd immunity" quickest will be fastest to recover, meaning that the virus spreads readily and renders most of the population immune.

As the opening bell approaches, stock futures have lost some of their momentum, but still point to a positive opening Friday, which also happens to be a quadruple witching day.

Investopedia.com defines quadruple witching as "...a date on which stock index futures, stock index options, stock options, and single stock futures expire simultaneously. While stock options contracts and index options expire on the third Friday of every month, all four asset classes expire simultaneously on the third Friday of March, June, September, and December."

These dates are normally volatile, but should fit snugly into the current trading regime.

At the Close, Thursday, March 19, 2020:
Dow Jones Industrial Average: 20,087.19, +188.29 (+0.95%)
NASDAQ: 7,150.58, +160.74 (+2.30%)
S&P 500: 2,409.39, +11.29 (+0.47%)
NYSE: 9,461.30, +76.71 (+0.82%)

Wednesday, February 5, 2020

Stocks Rock Higher, Look to Extend Rally on Coronavirus Treatments, Upbeat ADP Report

Tuesday's rally was the best since August of last year, as the spread of the coronavirus appeared to be centered in China and has not advanced with great intensity to the rest of the world. While the situation in China is still dire, with 494 deaths cumulative totaled worldwide as of Tuesday night, the number of cases reported outside of its epicenter appears to have been mostly contained. In the United States, confirmed cases is holding at 11, and the global total outside of China is just 216. That compares well to the number of confirmed cases inside China, at 24,391 and still growing.

There is a very good interactive map and graphical overview from John Hopkins, here.

Also encouraging is news on treatments for the disease on various fronts. Chinese researchers have applied for a patent to employ Gilead Science's Remdesivir as a treatment, which was used to treat the first US patient in Washington state in late January. The first known case of coronavirus in the US was treated with the drug and continues to recover.

In the US, the Department of Health and Human Services (HHS) is collaborating with Regeneron Pharmaceuticals on a coronavirus treatment.

These positive developments have driven stocks higher after a sudden collapse on the major indices last Friday.

Elsewhere, Nancy Pelosi, apparently still upset that Donald J. Trump is still president of the United States, tore up her copy of Trump's State of the Union speech, immediately after the president had delivered his positive message to the congress. Despite the hissy fit by Speaker of the House Pelosi, Mr. Trump's presidency appears to be sailing along nicely despite partisan Democrat attempts to derail it. The president is expected to be cleared of any wrongdoing on Wednesday at 4:00 pm ET, when the Senate will likely acquit him on impeachment charges brought by the House Democrats.

There was more good economic news prior to Wednesday's market open, as ADP reported January private sector job gains of 291,000, the largest upswing in four years.

Stock futures point to a positive open in New York.

At the Close, Tuesday, February 4, 2020:
Dow Jones Industrial Average: 28,807.63, +407.82 (+1.44%)
NASDAQ: 9,467.97, +194.57 (+2.10%)
S&P 500: 3,297.59, +48.67 (+1.50%)
NYSE: 13,862.84, +184.91 (+1.35%)